ABC Health Horizons

Scripps Research Institute, renowned for its work in drug development and medicinal chemistry, is making a bigger commitment to stem cell research.

The institute has created its own Center for Regenerative Medicine and has hired embryonic stem cell scientist Jeanne Loring away from the Burnham Institute to lead it.

Scripps President Richard Lerner and faculty leaders thought embryonic stem cell research would be a great addition to the institute. Scientists in an array of specialties at Scripps are using stem cells in their research.

But the institute did not have a leader in the field, someone to organize the different areas of stem cell work that were being done. It also lacked an organized stem cell organization, such as those operated by the three other big institutes in Torrey Pines – the University of California San Diego, Burnham and the Salk Institute.

Enter Loring, whose work explores the potential of embryonic stem cells to differentiate into the more than 200 cell types in the body, a trait that scientists hope may one day be used to treat diseases such as Parkinson’s, Alzheimer’s and diabetes.

She has a bachelor’s degree in molecular biology and a doctorate in developmental neurobiology. She has taught at the University of California Davis and held research and management posts at several biotechnology companies, including Incyte Genomics and Arcos BioScience, which is now part of San Diego-based stem cell company Novocell.

“This is an unbelievable opportunity because Scripps is known for its medicinal chemistry, and drugs can be tested on embryonic stem cells,” she said. “So there are things I can do here that I couldn’t do at Burnham.”

Researchers at the Scripps Center for Regenerative Medicine will explore many aspects of stem cells, including embryonic, adult and malignant cancer stem cells, from their basic biology to potential clinical applications in drug discovery, drug delivery and cell therapy.

The new center’s major mission is to provide infrastructure to support collaboration and strategic partnerships in human stem cell research and train the next generation of stem cell scientists, Loring said.

An intensive human embryonic stem cell laboratory course, sponsored by the National Institutes of Health, will be offered this fall, and the center will be the site of the San Diego-area training course supported by the California Institute for Regenerative Medicine.

“The potential of stem cell research is vast,” Lerner said. “It takes a scientist of Professor Loring’s foresight, knowledge and experience in basic and applied research to lead the institute’s team to new discoveries that will significantly benefit human health.”

Scripps Research Institute is already a member of the San Diego Consortium for Regenerative Medicine, a nonprofit collaborative body composed of scientists from the four major institutes in Torrey Pines.

Consortium members work in stem cells and other specialties expected to contribute to bringing stem cell-based therapies, diagnostics and drug discovery tools to market. For instance, Scripps’ medicinal chemistry expertise and UCSD’s engineering expertise are expected to be important components of the consortium.

1   Media publicity — you mean free advertising?

No. Publicity and advertising are two very distinct methods of marketing. With advertising, you pay for a specific space or time to get your message across a predetermined number of times. With publicity, you pay only the minimal costs of getting your message out to the media by phone, mail or fax. The media then may choose to disseminate your message, at their expense and at whatever time, setting and length they choose. Once you’ve pitched your story to the media, whether you receive a blizzard of publicity or none whatsoever you’re doing a great deal for your new small business.

2   Why would the media want to publicize my business?

If you know how to answer a key question — Why would our readers/listeners/viewers be interested in learning about you now? — they will be happy to use your story to fill up their airtime or column space. As a reporter once told a friend of mine, “The media are a hungry animal that needs to be constantly fed.” So the trick is to feed them an angle on your business that their particular audience will perceive as news, entertainment or useful information.

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Ann has a unique way of explaining things in her e-mails as follow-up to keep you interested in the process of network marketing. I especially liked one way she had to describe her system. A quote from Ann “I’m going to borrow a little word picture that Perry Marshall uses to describe it to you.

Have you ever driven a car with a stick shift at some point? Maybe you drive one right now. Anyone who’s ever driven a manual knows that the car needs to be in first gear in order to start it. That is, if you don’t want to get whiplash.

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Well it’s the same way with sales.

The problem is that most distributors try to start the whole process in 3^rd or 4^th or even 5^th gear. They do this by trying to close the prospect way too soon. This is damaging to both parties involved because the prospect immediately feels like they’re being backed into a corner, so they become defensive…..and…..the distributor has to deal with yet another rejection.”

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Watch for more information on this subject in the future.

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